Trialsphere

Participate in a Clinical Study in Chandler, Arizona

At TrialSphere Clinical Research (formerly MD First Research Chandler) in Chandler, Arizona, we welcome individuals and families who want to explore clinical research options for neurological and other health conditions. We partner with people across Arizona to advance care through carefully designed clinical studies led by an experienced team, with a primary focus on Dementia, Migraine, and Neuropathy, and
expanding into additional areas as new opportunities open. We follow strict ethical and regulatory standards so that every participant’s rights, safety, and privacy are respected. Your questions matter here, and we are committed to making research clear, supportive, and accessible, so you can decide with confidence whether participation is right for you.
Enroll Now and See If You Qualify
Participation is voluntary. You may withdraw at any time.

Participation Essentials

You may know us by our former name, MD First Research Chandler. We are now TrialSphere Clinical Research, with the same Arizona roots, the same experienced team, and the same commitment to compassionate, community based clinical research in Chandler and across the East Valley.
Clinical research can feel unfamiliar at first. Our role is to make the experience clear and supportive, to answer your questions with respect, and to help you decide what is right for you and your family. Every visit begins with listening.
TrialSphere Clinical Research connects patients with advancing care while supporting the discoveries that improve future health.
Our clinical studies are designed to answer important medical questions while caring for you as a person, not only as a participant.
What we offer:
  • Pioneering clinical studies in the heart of Arizona
  • Expertise in neurological wellness among other areas of care
  • A broad spectrum of enrolling and forthcoming clinical studies
  • Opportunities to access innovative therapies before they are widely available
Every study is different, and eligibility varies. We will explain options clearly and recommend a study only when it fits health needs and goals.

People participate in clinical research for many reasons, including hope for better options, interest in new approaches, and the desire to help future patients.

Participants often value:
  • Around the clock access to our dedicated healthcare team for support during the study
  • Opportunities for enhanced health monitoring and follow up
  • The chance to contribute to medical advancements that may improve future care
A clinical study may or may not help a condition directly. Participation helps build knowledge that can improve care for others.
We guide you step by step, with clear information and no pressure.
  • 1. Start with a conversation: Complete the interest form or contact our team directly
  • 2. Eligibility review: A coordinator reviews your health history and the study requirements
  • 3. Screening visit: If appropriate, an in clinic visit is scheduled to confirm eligibility
  • 4. Informed consent: We explain the study purpose, procedures, risks, benefits, and alternatives before you decide
  • 5. Study visits and ongoing support: A clear visit schedule is provided, with a team available for questions
  • 6. Follow up and next steps: When the study ends, outcomes are reviewed and next steps are discussed
Participation remains voluntary throughout the study.
Your safety is the foundation of every study. Clinical research follows strict ethical and regulatory standards, and each study is reviewed and monitored to protect participants.
You can expect:
  • Privacy and confidentiality strictly safeguarded
  • Clear answers to questions before and during participation
  • Freedom to withdraw at any time without penalty or loss of care
We are committed to keeping the research experience clear, supportive, and accessible.
Eligible participants may receive reimbursement for time and travel. Transportation assistance may be available depending on the study. Reimbursement details are reviewed before participation begins.

For detailed information about how clinical studies work, visit the Research Studies Page.

Enroll Now and See If You Qualify

Current Studies

Sonusmed Hypertension Study (HIGH BLOOD PRESSURE)

  • Adults aged 21-75 with hypertension (≥140/90 mmHg)
  • Diagnosed with high blood pressure on at least three separate occasions
  • NOT taking more than one antihypertensive medication
  • NOT using weight loss medications (e.g., Ozempic, Mounjaro)
Sign Up

Chronic Low Back Pain Study (Obesity/Overweight)

  • Adults 18+ with chronic low back pain and BMI 35 or higher
  • Pain stays in lower back or upper legs, not from other causes
  • Tried and failed to lose weight by dieting
  • No recent injections, weight loss meds, major weight change, or diabetes
Sign Up

Early Alzheimer’s Study

  • Adults 18+ with chronic low back pain and BMI 35 or higher
  • Pain stays in lower back or upper legs, not from other causes
  • Tried and failed to lose weight by dieting
  • No recent injections, weight loss meds, major weight change, or diabetes
Sign Up

Menstrual Migraine Study

  • 18 years or older
  • At least 1-year history of migraine with or without aura
  • Regular menstrual cycles
  • Less than 15 headache days per month on average
Sign Up

Episodic/ Chronic Migraine Study

  • Must be 18 or older with a history of migraines for over 12 months
  • Must have fewer than 15 headache days per month and six or more migraine days
  • No recent use of Botox, certain migraine medications, or opioids
Sign Up

Upcoming Studies

  • Axsome: Menstrual Migraine Study
  • Eli Lilly: Early Alzheimer's Study
  • Merz Therapeutics: Xeomin® for the Prevention of Chronic Migraine
  • Merz Therapeutics: Xeomin® for the Prevention of Episodic Migraine
Sign Up

Migraines

Multiple
Sclerosis

Painful Diabetic Neuropathy

Parkinson’s
Disease

Stories And Updates

Clinical research is always moving forward, and so are we. This space will share the latest news from TrialSphere Clinical Research, including new clinical studies and other updates that may be helpful to participants, families, and the Chandler community.

WHAT May be Featured

  • New clinical studies and enrollment opportunities
  • Research updates and milestones
  • Educational resources and wellness insights
  • Community events and announcements
Read the Blog

Get Involved

There are several ways to get involved with TrialSphere Clinical Research. Upcoming educational and community events are listed on the Home page and offer a welcoming way to learn more about current and future studies. Questions about participation can be submitted through the Contact Us page. For study specific questions, the Ask An Expert MailChimp form is available. Social media channels provide an easy way to stay connected with updates, announcements, and new research opportunities, and the Newsletter sign up option offers periodic study updates delivered directly to inboxes.